> Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer's disease.
Tan Z, et al. Among authors: cogram p. Acta Neuropathol Commun. 2022.
> Genome Sequencing Variations in the Octodon degus, an Unconventional Natural Model of Aging and Alzheimer's Disease.
Hurley MJ, et al. Among authors: cogram p. Front Aging Neurosci. 2022.
> Genome sequencing variations in the Octodon degus, an unconventional natural model of aging and Alzheimer's disease.
Michael J Hurley, Claudio Urra, Bernardo M Garduno, Agostino Bruno, Allison Kimbell, Brent Wilkinson, Cristina Marino-Buslje, Marcelo Ezquer, Fernando Ezquer, Pedro Francisco Fernandez Aburto, Elie Poulin, Rodrigo A Vásquez, Robert Deacon, Ariel Ávila, Francisco Altimiras, Peter Vanderklish, Claudio Angione, Guido Zampieri, Gabriele Constantino, Todd C Holmes, Marcelo Pablo Coba, Xiangmin Xu, Patricia Cogram
Frontiersin Aging Neuroscience, section Alzheimer's Disease and Related Dementias, 2022.
> Spatial maps and oscillations in the healthy hippocampus of Octodon degus, a natural model of sporadic Alzheimer's disease.
Mugnaini M, Polania D, Diaz Y, Ezquer M, Ezquer F, Deacon RMJ, Cogram P, Kropff E.
Sci Rep. 2022 May 5;12(1):7350. doi: 10.1038/s41598-022-11153-4.
> Dementia in Latin America: Paving the way toward a regional action plan.
Parra MA et. al.
Alzheimers Dement. 2021 Feb;17(2):295-313. doi: 10.1002/alz.12202. Epub 2020 Nov 2021
> Editorial: Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America.
Ibáñez A, Sedeño L, García AM, Deacon RMJ, Cogram P.
Front Aging Neurosci. 2018 Apr 6;10:95. doi: 10.3389/fnagi.2018.00095. eCollection 2018.
PMID: 29681845
> Natural AD-Like neuropathology in Octodon degus: impaired burrowing and neuroinflammation
Robert MJ Deacon, Francisco J Altimiras, Enrique A Bazan-Leon, Rhada D Pyarasani, Fabiane M Nachtigall, Leonardo S Santos, Anthony G Tsolaki, Lina Pednekar, Uday Kishore, Rodolfo R Biekofsky, Rodrigo A Vasquez, Patricia Cogram
> The long-lived Octodon degus as a rodent drug discovery model for Alzheimer's and other age-related diseases
Michael J Hurley, Robert MJ Deacon, Katrin Beyer, Elena Ioannou, Agustin Ibáñez, Jessica L Teeling, Patricia Cogram
> Brain transcriptome sequencing of a natural model of Alzheimer's disease
Francisco Altimiras, Barbara Uszczynska-Ratajczak, Francisco Camara, Anna Vlasova, Emilio Palumbo, Stephen Newhouse, Robert MJ Deacon, Leandro AE Farias, Michael J Hurley, David E Loyola, Rodrigo A Vásquez, Richard Dobson, Roderic Guigó, Patricia Cogram
Human and animal models for translational research on neurodegeneration: Challenges and opportunities from South America
Agustín Ibáñez, Lucas Sedeño, Adolfo M García, Robert MJ Deacon, Patricia Cogram
> Evaluation of the rodent Octodon degus as a pre-clinical model of liver fibrosis
S Brockbank, P Cogram, D Leeming, ST Hjuler, S Cruwys
